Pseudotraining suppressed stimulus-evoked responses in individual neurons: (A) example FOV with cell masks. Color indicates the difference between the corresponding peak responses across responsive trials for individual cells on ACC4–5 and ACC5–6. (B) Cumulative distribution of stimulus-evoked peak response across responsive trials on ACC5 (black curve) and ACC6 (gray curve). Kolmogorov–Smirnov test: P = 0.86; Wilcoxon signed-rank test: P = 0.38. (C) Mean peak responses of individual cells on ACC6 (gray dots) ranked from the weakest to the strongest based on the mean responses of the same cells across responsive trials on ACC5 (black dots). Each dot represents the stimulus-evoked response of a cell (N = 6 mice; n = 173 cells). Dots indicate cells with more than a twofold increase on the later training day in comparison with the earlier training day. Circles indicate the rest of the cells. Pie chart indicates the percentage of cells showing greater than twofold increase (blue). (D–L) As in A–C, but for cell responses on ACC6 versus PSE1, ACC6 versus PSE5, and ACC6 versus PSE10, respectively. Red dots indicate the same cells with greater than twofold increase on PSE1, 5, and 10. P values of Kolmogorov–Smirnov test and Wilcoxon signed-rank test in figures.
