Perirhinal cortex and feature-ambiguous discriminations
- Timothy J. Bussey1,3,
- Lisa M. Saksida1, and
- Elisabeth A. Murray2
- 1 Department of Experimental Psychology, University of Cambridge, Cambridge CB1 3EB, United Kingdom;
- 2 Laboratory of Neuropsychology, National Institute of Mental Health, NIH, Bethesda, Maryland 20892, USA
This extract was created in the absence of an abstract.
Perirhinal cortex is often regarded as part of a medial temporal lobe (MTL) memory system, mediating memory selectively, and having little role in other functions such as perception (e.g., Squire and Zola-Morgan 1991; Buffalo et al. 1998, 1999; Squire et al. 2004). We and others have argued against this idea, suggesting instead that perirhinal cortex may have a role in perception (e.g., Buckley and Gaffan 1997; Murray and Bussey 1999; Buckley et al. 2001; Bussey and Saksida 2002). Evidence to support this view has come from recent work indicating that lesions of perirhinal cortex can impair the discrimination of visual stimuli. Perirhinal cortex is not, however, important for all types of visual discrimination (Buckley and Gaffan 1997; Hampton and Murray 2002), only for those requiring representations of complex conjunctions of features (Saksida and Bussey 1998; Murray and Bussey 1999; Buckley et …
