Figure 7.
Sex-specific cellular pathways targeted by M1 polyubiquitination in the amygdala at 2 and 4 h after contextual fear conditioning. Utilizing QIAGEN IPA pathway analysis software, we analyzed our M1 polyubiquitination targets to determine cellular pathways targeted by this modification. Targeted pathways are displayed on the left with −log (P-value) being displayed on the top. Threshold displayed in orange is set to a P-value of <0.05, which equated to a −log (P-value) of 1.3. Pathways targeted at 2 h by males (A) and females (B) and pathways targeted at 4 h by males (C) and females (D) are displayed.
