Figure 3.
K48 polyubiquitination targets change in a sex- and time-dependent manner in the amygdala following contextual fear conditioning. (A) Utilizing previously published proteomic data for 1 h after fear conditioning (Farrell et al. 2021) publicly available with PRIDE accession number PXD027544, we compared the total number of significantly altered K48 polyubiquitin targets across the memory consolidation window to establish a temporal pattern by sex. (B) We then separated the significantly changed targets by positive and negative log2 fold changes to establish a further understanding of the temporal dynamics.
