Using a socially enriched environment test to evaluate the effects of different therapeutic approaches on social behavior in a mouse model of social anxiety disorder

Effect of extinction training. (A) Duration of object exploration. (B) Individual exploration preference index. (C) Time of social interaction. (D) Freezing time. Results are presented as means ± SEM. Holm-Šídák post hoc test. n(SFC−) = 6, n(SFC+) = 5. (##) P < 0.01; (###) P < 0.001 versus SFC−. (++) P < 0.01; (+++) P < 0.001 versus OPZ exploration. (*) P < 0.05; (**) P < 0.01; (***) P < 0.001 versus SEE. ($) P < 0.05; ($$) P < 0.01; ($$$) P < 0.001 versus SEE+EXT1. (OPZ) Outside a proximity zone, (IPZ) inside a proximity zone, (EXT) extinction.