Figure 4.
Open field data. (A) Schematic of open field test, with outer edge (purple) and center (red) highlighted. (B) A significant group × sex interaction was observed for the number of center entries, with female Apoe mice making less center entries than controls, and male Apoe mice making more center entries than controls (F(1,4) = 7.581, P = 0.0126). (C–E) There were no statistically significant differences in the amount of time spent in the center (C), time spent freezing (D), or total distance traveled (E) as a function of group or biological sex. Error bars represent the standard error of the mean; dots are individual data points.
