Overexpression of the Apoe gene in the frontal cortex of mice causes sex-dependent changes in learning, attention, and anxiety-like behavior

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Figure 1.
Figure 1.

Experimental design and number of sessions needed to reach learning criteria for the rCPT. (A) Chamber design. (B) Experimental design and surgery schematic. (C) Description of rCPT stages. (D) There were no significant differences in the number of sessions needed to reach criteria on stage 1 between group (Apoe vs. EGFP controls) or sex. (E) There were no significant differences in the number of sessions needed to reach the criteria on stage 2 between group or sex. (F) There were no significant differences in the number of sessions needed to reach criteria on stage 3 between group or sex. Error bars represent the standard error of the mean; dots are individual data points.

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