Reactivation-dependent transfer of fear memory between contexts requires M1 muscarinic receptor stimulation in dorsal hippocampus of male rats

Illustration of the FRaT task. Rats undergo a training session in which they receive three footshocks. The reactivation session occurs 24 h later and lasts 90 sec in the fear conditioning chambers. Animals are exposed immediately after to either a circular or triangular alternate context for 8 min before being returned to their home cages. Twenty-four hours later, they are assessed for freezing in either the same alternate context as the day before, a different alternate context, or the original fear conditioning chamber for a period of 8 min.