Reactivation-dependent transfer of fear memory between contexts requires M1 muscarinic receptor stimulation in dorsal hippocampus of male rats

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Figure 3.
Figure 3.

The transfer of fear to alternate contexts is reactivation-dependent. (A) During the reactivation (RA) session, there was no significant difference in freezing behavior between the groups in the alternate contexts. Freezing behavior was measured as percent freezing (±SEM) across an 8 min post-reactivation session in the alternate contexts. (B) For the test session, the group that was reexposed to the fear conditioning chamber during the reactivation session (Same-RA) froze significantly higher in the alternate context than the group that was not exposed to the chamber (Same-NoRA). Freezing behavior (n = 7 per group) was measured as percent freezing (±SEM) across an 8 min test session. (**) P < 0.01.

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