Standardized extract of Ginkgo biloba treatment and novelty on the weak encoding of spatial recognition memory in rats

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Figure 1.
Figure 1.

Schematic representation of the procedure for acquisition and retrieval of the object location memory (OLM) task. Young adult rats were allowed to freely explore the sample objects (A and B) for 15 min (strong training [ST]) or for 5 min (weak training [WT]). (AD) Memory retention was evaluated 1 h (short-term memory [STM]) or 24 h (long-term memory [LTM]) after the training session. The mean discrimination index (DI) and recognition index (RI) of the sample objects were evaluated on training session for WT and ST groups. Mean DI (A,C) and RI (B,D) of the moved and sample objects were evaluated on STM (A,B) and on LTM (C,D) (n = 8–7 per group/time probe test). All individual values are shown. The values are presented as the means (±SEMs). The horizontal lines represent the chance value for the DI (0.0) and for RI (0.5). Blue significant P-values represent the ratio discriminations from the group above chance level, according to one-sample t-tests. Intragroup comparisons (testing vs. training sessions) used a paired t-test.

This Article

  1. Learn. Mem. 30: 85-95