O-GlcNAc and EZH2-mediated epigenetic regulation of gene expression during consolidation of fear memories

EZH2 protein is dynamically regulated by OGT. (A) Schematic of intra-CA1 siRNA infusion followed by training in contextual fear conditioning. (B) Quantification of EZH2 western blots (n = 6, 6, 5; One-way ANOVA with Fisher's exact test, * denotes P < 0.05) (C) RT-qPCR quantification of (C) Ezh2 mRNA (n = 4, 5, 5; One-way ANOVA with Fisher's exact test).