Construction and disruption of spatial memory networks during development

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Figure 6.
Figure 6.

eFSE provokes persistent impairment of spatial memory in active avoidance which is abrogated by blocking NRSF after eFSE (Patterson et al. 2017). (A) eFSE rats treated with a SCR ODN received more shocks than both control groups (CTL + SCR ODN, CTL + NRSE ODN), as well as from eFSE rats treated post hoc with a blocker of NRSF (eFSE + NRSE ODN). (B) Similar results are obtained when assessing the duration of time spent in the opposite quadrant to the shock zone. The eFSE + SCR group spent less time in the opposite quadrant than the other three groups. (C) Representative traces of movement of rats from each of the four groups.

This Article

  1. Learn. Mem. 26: 206-218