Comparison of the ionic currents modulated during activity-dependent and normal presynaptic facilitation

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Figure 4.
Figure 4.

The depolarizing voltage clamp pulse can also act as the CS during training. (A) Example of a training trial with a 500 msec, 20 mV depolarizing voltage clamp pulse as the paired and unpaired CS instead of a brief train of action potentials. (B) Average testing results from 12 experiments like the one shown in A. There was a significantly greater decrease in the net outward current in the paired than the unpaired SN after training with a depolarizing voltage clamp pulse as the CS.

This Article

  1. Learn. Mem. 26: 449-454