Effect of SPS and emotional learning/memory on c-Fos and c-Jun levels in the PAG. (A) FC enhanced c-Fos expression in all PAG regions and enhanced c-Fos signal values during extinction training in the dmPAG and lPAG. SPS had no effect on c-Fos expression in any PAG region. (B) SPS decreased basal levels of c-Jun in the dmPAG and possibly decreased basal levels of c-Jun in the lPAG (effect approached significance). SPS also enhanced c-Jun expression (relative to controls) during ExtTrain and ExtTest in the vPAG, during all behavioral sessions in the dmPAG, and during ExtTest in the lPAG. Black * represents the effects of learning while red * represents the effects of stress. All * are for statistical comparisons at P < 0.05 criterion.
