Memory destabilization is critical for the success of the reactivation–extinction procedure

Experiment 4. (A) Experimental protocol. Seventy-two hours after contextual fear conditioning, rats were exposed to the training context for 4 min. Six hours later, rats were returned to the training context for an 11-min extinction session (R4/E11 6 h). Rats were evaluated 24 h later in a 5-min test and again 7 d later in a retest. (B) Data are the mean ± SEM of percentage time spent freezing during reactivation, test, and retest.