Mice overexpressing type 1 adenylyl cyclase show enhanced spatial memory flexibility in the absence of intact synaptic long-term depression

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Figure 5.
Figure 5.

AC1 TG mice show stronger new memory formation than WT mice. (A) Morris water maze training protocol. (B) Improvement of escape latency during the visible platform, hidden platform, and reversal platform training. (C) Percentage of time spent in each quadrant during the first probe test (after hidden platform training) and the second probe test (after the reversal platform training). (D) Number of crossing over the target platform location during the first and the second probe tests. As indicated by the filled circle, the platform location was in quadrant 1 during the hidden platform training, and in quadrant 3 during the reversal training. (*) P < 0.05; (ns) not significant.

This Article

  1. Learn. Mem. 20: 352-357