Mice overexpressing type 1 adenylyl cyclase show enhanced spatial memory flexibility in the absence of intact synaptic long-term depression

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Figure 2.
Figure 2.

Mice overexpressing AC1 show impaired LTD in vivo. The extracellular fEPSP at the Shaffer collateral/CA1 synapses was recorded from anesthetized animals. LFS (900 pulses at 1 Hz) induces significant synaptic depression in WT but not AC1 TG mice.

This Article

  1. Learn. Mem. 20: 352-357

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