Social recognition memory requires two stages of protein synthesis in mice

Table 1.

Number of Fos-positive cells counted in distinct brain areas of the accessory and main olfactory systems in adult male mice under control conditions or in response to juvenile exposure after different survival times


Brain area

Control

70 min

2 h

4 h

6 h

7 h
Accessory olfactory bulb Granular cells 6.8 ± 2.4b 91 ± 45a 64.3 ± 40a 26.3 ± 15b′ 16.3 ± 12b 9.17 ± 6.6b
Mitral cells 7.8 ± 4.4b 44 ± 29a′ 55.8 ± 18a 29.8 ± 21b″ 14.3 ± 2.5b′ 5.5 ± 2.4b
Medial amygdala 13 ± 4.2b 45 ± 18a 43.5 ± 4a 16 ± 6.1b 9.67 ± 3.5b 8.67 ± 2.4b
Medial preoptic area 6.8 ± 4.7b 22 ± 5.7a 19.7 ± 8.1a 18.7 ± 4.7a 7.33 ± 1.5b 4.5 ± 1.9b
Main olfactory bulb 28 ± 9.8b 75 ± 27a 30.8 ± 11b 27.8 ± 14b 30.7 ± 9.3b 12 ± 2.8b
Piriform cortex

11 ± 8.1c
24 ± 8a
17 ± 3.6b
5.33 ± 2c
5.33 ± 2.3c
5.33 ± 2.3c
  • Data are means ± S.E.M.

  • a P < 0.01 vs. b and c and P < 0.05 vs. b′ and b″

  • a′ P < 0.01 vs. b and P < 0.05 vs. b′

  • b P < 0.01 vs. c, ANOVA followed by Fisher's-LSD test

This Article

  1. Learn. Mem. 12: 407-413