Social recognition memory requires two stages of protein synthesis in mice

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Figure 3.
Figure 3.

Effects of anisomycin (ANI) on olfactory recognition memory performance of adult male mice as tested in the social discrimination procedure. ANI was injected subcutaneously (150 mg/kg body wt.; ▾) 20 min before sampling on (A) the total investigatory curiosity and (B) juvenile discrimination at an RI of 60 min. During the control session the animals received the same volume of sterile NaCl solution (0.9 %; NaCl, ▿). (A) ANI treatment significantly reduced the investigatory curiosity per se, but (B) did not affect juvenile discrimination. *P < 0.05, ***P < 0.001, paired Student's t-test.

This Article

  1. Learn. Mem. 12: 407-413